General Cell Based Assays
Cambridge Isotope Laboratories GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
Abcam Chymotrypsin Assay Kit (Fluorometric)
Chymotrypsin Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress NMBR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0925E2CP2M)
The PathHunter NMBR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuromedin B) based activation of NMBR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NMBR and EA-tagged β-Arrestin-2. Activation of NMBR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR120S (Short Isoform) CHO-K1 β-Arrestin GPCR Assay, 2-plate Kit. (93-0924E2CP0M)
The PathHunter GPR120S eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. free fatty acids) based activation of GPR120S GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR120S and EA-tagged β-Arrestin-2. Activation of GPR120S stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CXCR6 Total Internalization Assay, 2pl Kit. (93-0886E3CP0M)
The PathHunter CXCR6 Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CXCR6 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CXCR6 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CXCR6 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress F2RL1 (PAR2; GPR11) HEK 293 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0235E1CP0L)
The PathHunter F2RL1 (PAR2; GPR11) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. proteases, SLIGRL) based activation of F2RL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged F2RL1 and EA-tagged β-Arrestin-2. Activation of F2RL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress SSTR3 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0244E2CP0M)
The PathHunter SSTR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR3 and EA-tagged β-Arrestin-2. Activation of SSTR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CALCRL-RAMP2 (AM1) CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0270E2CP0L)
The PathHunter CALCRL-RAMP2 (AM1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. adrenomedullin) based activation of CALCRL GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CALCRL and EA-tagged β-Arrestin-2, along with untagged modulating protein RAMP2. Activation of CALCRL stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery RPLEX HUM IL28BIFN 3 ASY
The R-PLEX Human IL-28B (IFN-lambda3) Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that enables the quantitative measurement of human interleukin 28B (IL-28B) also known as interferon lambda 3 (IFN-lambda3) This assay utilizes MSD s electrochemiluminescent detection technology and is provided in a 96-well plate format The assay has a detection range of 0 03-1000 pg/mL and requires 50 L of sample per well This product can be used to measure IL-28B levels in serum plasma and cell culture supernatants IL-28B is a cytokine that has antiviral activity and is involved in immune response against viruses
Meso Scale Discovery U-PLEX Mouse IL-13 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IL-13 Assay Kit is a multiplex immunoassay that allows simultaneous measurement of mouse interleukin 13 (IL-13) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision The kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL compound calibrators controls 10X diluent read buffer wash buffer and adhesive plate seals The assay has a typical sensitivity of 0 3 pg/mL and an upper limit of quantification of 10 000 pg/mL for mouse IL-13
Meso Scale Discovery U-PLEX Mouse IL-9 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IL-9 Assay Kit is an electrochemiluminescent immunoassay for the quantitative measurement of mouse interleukin 9 (IL-9) in serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible quantitation of mouse IL-9 with a lower limit of detection of 0 3 pg/mL and an upper limit of 10 000 pg/mL The kit includes a 96-well plate coated with capture antibody detection antibody conjugated to MSD SULFO-TAG calibrators and sample diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation
Eurofins Discoverx PathHunter eXpress TACR3 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0501E2CP2M)
The PathHunter TACR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. substance P, senkitide) based activation of TACR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR3 and EA-tagged β-Arrestin-2. Activation of TACR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HRH3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0509E2CP2L)
The PathHunter HRH3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH3 and EA-tagged β-Arrestin-2. Activation of HRH3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress P2RY6 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0500E2CP19M)
The PathHunter P2RY6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY6 and EA-tagged β-Arrestin-2. Activation of P2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.